mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab00117(ACTA2 antibody) at dilution of 1:1000
IP Result of anti-ACTA2/smooth muscle actin (IP:FNab00117, 3ug; Detection:FNab00117 1:1000) with mouse liver tissue lysate 6000ug.
Immunohistochemistry of paraffin-embedded human liver cancer tissue using FNab00117(ACTA2 antibody) at dilution of 1:50
Background
ACTA2(also known as α-smooth muscle actin or α-SMA) belongs to the actin family. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 is primarily expressed in vascular smooth muscle and anti-ACTA2 is commonly used to marker smooth muscle cells. This antibody may cross-react with other isoforms of actins.